A multiclostridial vaccine for cattle and sheep from 2 weeks of age to prevent mortality, lesions and clinical signs of disease caused by Clostridium perfringens type A (haemorrhagic enteritis), C. perfringens type B (lamb dysentery), C. perfringens type C (necrotic enteritis), C. perfringens type D (pulpy kidney), C. chauvoei (black quarter), C. novyi type B, C. septicum (malignant oedema), C. tetani (tetanus), C. sordellii (sudden death syndrome) and C. haemolyticum (C. novyi type D).